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Proceedings Paper

Hybrid optoacoustic and ultrasonic imaging system for detection of prostate malignancies
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Paper Abstract

Ultrasound imaging is the current gold standard for guiding biopsy of prostate. Optoacoustic imaging yields higher contrast in detection of malignant tissues. The two techniques provide complementary information. We are currently developing a hybrid laser optoacoustic and ultrasound imaging system for prostate tumor detection (LOUIS-P). The optoacoustic part consists of a fiber-coupled Q-switched laser operating at either 757 nm or 1064 nm attached to a commercially-available 128-channel ultrasonic probe modified for optimal detection of optoacoustic signals, a digital signal processor with 128 independent channels, and software that uses the radial (filtered) backprojection algorithm to reconstruct tomographic images. We evaluated system-imaging performance using test objects submerged in milky water, and poly(vinyl-chloride) plastisol tissue phantoms simulating malignant lesions. LOUIS-P demonstrates potential as a clinical technique for minimally invasive imaging and diagnosis of prostate cancer.

Paper Details

Date Published: 28 February 2008
PDF: 11 pages
Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68560T (28 February 2008); doi: 10.1117/12.769881
Show Author Affiliations
Mohammad A. Yaseen, Rice Univ. (United States)
H. P.-F. Brecht, Fairway Medical Technologies, Inc. (United States)
Sergey A. Ermilov, Fairway Medical Technologies, Inc. (United States)
Reda R. Gharieb, Fairway Medical Technologies, Inc. (United States)
Andre Conjusteau, Fairway Medical Technologies, Inc. (United States)
Alexander A. Oraevsky, Fairway Medical Technologies, Inc. (United States)


Published in SPIE Proceedings Vol. 6856:
Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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