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Proceedings Paper

The effects of respiration motion in PET/CT studies
Author(s): Lu Wan; Zhijian Wu; Fengyin Zhou; Sheng Ye; Shaoqun Zeng; Chien-Min Kao; Chin-Tu Chen; Yongxue Zhang; Qingguo Xie
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Paper Abstract

In recent years, the clinical status of positron emission tomography(PET)/computed tomography(CT) in achieving more accurate staging of lung cancer has been established and the technology has been enthusiastically accepted by the medical community. However, its capability in chest imaging is still limited by several physical factors. As a result of typical PET/CT imaging protocol, respiration-averaged PET data and free of respiration-averaged CT data are collected in a PET/CT scanning. In this work, we investigate the effects of respiration motion. We employ mathematical and Monte-Carlo simulations for generating PET/CT data. We scale a Zubal phantom to generate 30 phantoms having various sizes in order to represent different torso anatomic states during respiration. Images reconstructed from selected scaling PET data using the respective scaling PET attenuation maps serve as baseline results. PET/CT imaging protocol is simulated by reconstruction from respiration-averaged PET data with the selected PET attenuation maps. We also reconstruct PET images from respiratory-averaged PET data with respiration-averaged PET attenuation maps, which simulates conventional PET imaging protocol. We will compare the resulting images reconstructed from the above-mentioned approaches to evaluate the effects of respiration motion in PET/CT.

Paper Details

Date Published: 18 March 2008
PDF: 6 pages
Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69134A (18 March 2008); doi: 10.1117/12.769705
Show Author Affiliations
Lu Wan, Huazhong Univ. of Science and Technology (China)
Hubei Province Key Lab. of Molecular Imaging (China)
Zhijian Wu, Hubei Province Key Lab. of Molecular Imaging (China)
Huazhong Univ. of Science and Technology (China)
Fengyin Zhou, Huazhong Univ. of Science and Technology (China)
Hubei Province Key Lab. of Molecular Imaging (China)
Sheng Ye, Huazhong Univ. of Science and Technology (China)
Shaoqun Zeng, Huazhong Univ. of Science and Technology (China)
Chien-Min Kao, The Univ. of Chicago (United States)
Chin-Tu Chen, The Univ. of Chicago (United States)
Yongxue Zhang, Hubei Province Key Lab. of Molecular Imaging (China)
Huazhong Univ. of Science and Technology (China)
Qingguo Xie, Huazhong Univ. of Science and Technology (China)
Hubei Province Key Lab. of Molecular Imaging (China)
The Univ. of Chicago (United States)


Published in SPIE Proceedings Vol. 6913:
Medical Imaging 2008: Physics of Medical Imaging
Jiang Hsieh; Ehsan Samei, Editor(s)

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