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Proceedings Paper

4DCT image-based lung motion field extraction and analysis
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Paper Abstract

Respiratory motion is a complicating factor in radiation therapy, tumor ablation, and other treatments of the thorax and upper abdomen. In most cases, the treatment requires a demanding knowledge of the location of the organ under investigation. One approach to reduce the uncertainty of organ motion caused by breathing is to use prior knowledge of the breathing motion. In this work, we extract lung motion fields of seven patients in 4DCT inhale-exhale images using an iterative shape-constrained deformable model approach. Since data was acquired for radiotherapy planning, images of the same patient over different weeks of treatment were available. Although, respiratory motion shows a repetitive character, it is well-known that patient's variability in breathing pattern impedes motion estimation. A detailed motion field analysis is performed in order to investigate the reproducibility of breathing motion over the weeks of treatment. For that purpose, parameters being significant for breathing motion are derived. The analysis of the extracted motion fields provides a basis for a further breathing motion prediction. Patient-specific motion models are derived by averaging the extracted motion fields of each individual patient. The obtained motion models are adapted to each patient in a leave-one-out test in order to simulate motion estimation to unseen data. By using patient-specific mean motion models 60% of the breathing motion can be captured on average.

Paper Details

Date Published: 11 March 2008
PDF: 11 pages
Proc. SPIE 6914, Medical Imaging 2008: Image Processing, 69141L (11 March 2008); doi: 10.1117/12.769407
Show Author Affiliations
Tobias Klinder, Univ. Hannover (Germany)
Philips Research Europe - Hamburg (Germany)
Cristian Lorenz, Philips Research Europe - Hamburg (Germany)
Jens von Berg, Philips Research Europe - Hamburg (Germany)
Steffen Renisch, Philips Research Europe - Hamburg (Germany)
Thomas Blaffert, Philips Research Europe - Hamburg (Germany)
Jörn Ostermann, Univ. Hannover (Germany)


Published in SPIE Proceedings Vol. 6914:
Medical Imaging 2008: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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