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Proceedings Paper

Studying the effect of noise on the performance of 2D and 3D texture measures for quantifying the trabecular bone structure as obtained with high resolution MR imaging at 3 tesla
Author(s): Roberto Monetti; Jan Bauer; Dirk Mueller; Ernst J. Rummeny; Thomas M. Link; Sharmila Majumdar; Maiko Matsuura; Felix Eckstein; Irina Sidorenko; Christoph W. Raeth
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Paper Abstract

3.0 Tesla MRI devices are becoming popular in clinical applications since they render images with a higher signal-tonoise ratio than the former 1.5 Tesla MRI devices. Here, we investigate if higher signal-to-noise ratio can be beneficial for a quantitative image analysis in the context of bone research. We performed a detailed analysis of the effect of noise on the performance of 2D morphometric linear measures and a 3D nonlinear measure with respect to their correlation with biomechanical properties of the bone expressed by the maximum compressive strength. The performance of both 2D and 3D texture measures was relatively insensitive to superimposed artificial noise. This finding suggests that MR sequences for visualizing bone structures at 3T should rather be optimized to spatial resolution (or scanning time) than to signal-to-noise ratio.

Paper Details

Date Published: 26 March 2008
PDF: 9 pages
Proc. SPIE 6914, Medical Imaging 2008: Image Processing, 69144U (26 March 2008); doi: 10.1117/12.769161
Show Author Affiliations
Roberto Monetti, Max-Planck-Institut für extraterrestrische Physik (Germany)
Jan Bauer, Technische Univ. München (Germany)
Dirk Mueller, Technische Univ. München (Germany)
Ernst J. Rummeny, Technische Univ. München (Germany)
Thomas M. Link, Univ. of California, San Francisco (United States)
Sharmila Majumdar, Univ. of California, San Francisco (United States)
Maiko Matsuura, Ludwig-Maximilians-Univ. (Germany)
Felix Eckstein, Paracelsus Medical Univ. (Austria)
Irina Sidorenko, Max-Planck-Institut für extraterrestrische Physik (Germany)
Christoph W. Raeth, Max-Planck-Institut für extraterrestrische Physik (Germany)


Published in SPIE Proceedings Vol. 6914:
Medical Imaging 2008: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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