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Proceedings Paper

A microfluidic chemical/biological sensor based on dissolvable membrane incorporating gold nanoparticles and optical absorption
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Paper Abstract

We present a microfluidic chemical/biological sensor based on dissolvable membranes incorporating gold nanoparticles. The presence of the target analyte in a fluidic sample being assayed dissolves the membrane, causing the change in its optical absorption. To enhance the contrast between the membrane and the fluidic sample, the membranes are chemically treated to exhibit strong absorption at certain wavelengths. Here, we use N,N'-cystaminebisacrylamide (CBA) cross-linked poly(acrylamide) (PAAm) membranes dissolved by a sample solution containing dithioerythritol (DTT) to demonstrate this approach. The dissolvable membrane incorporates gold nanoparticles to exhibit strong absorption at 572nm.

Paper Details

Date Published: 6 February 2008
PDF: 9 pages
Proc. SPIE 6885, MEMS/MOEMS Components and Their Applications V. Special Focus Topics: Transducers at the Micro-Nano Interface, 688507 (6 February 2008); doi: 10.1117/12.768715
Show Author Affiliations
Chi-Wei Lo, Univ. of Wisconsin-Madison (United States)
Sudheer S. Sridharamurthy, Univ. of Wisconsin-Madison (United States)
Hongrui Jiang, Univ. of Wisconsin-Madison (United States)


Published in SPIE Proceedings Vol. 6885:
MEMS/MOEMS Components and Their Applications V. Special Focus Topics: Transducers at the Micro-Nano Interface
Srinivas A. Tadigadapa; Babak A. Parviz; Albert K. Henning, Editor(s)

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