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Proceedings Paper

Divided shifted Raman spectroscopy for carotenoid detection
Author(s): S. D. Bergeson; J. B. Peatross; N. J. Eyring; J. F. Fralick; S. B. Ferguson
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Paper Abstract

We have developed a compact portable instrument for resonance Raman spectroscopy of carotenoid molecules in skin tissue. Our application focuses on the 1525 cm-1 Raman line common to all carotenoids. We use a divided shifted Raman spectroscopy (DSRS) technique that reduces sensitivity to detector drift and error. Two wavelength-narrowed LEDs illuminate the sample, and scattered light in four different wavelength channels is measured. This multi-spectral approach has single-photon sensitivity and compares favorably with laser-based Raman measurements in terms of accuracy, repeatability, and measurement time.

Paper Details

Date Published: 8 February 2008
PDF: 8 pages
Proc. SPIE 6853, Biomedical Optical Spectroscopy, 68530A (8 February 2008); doi: 10.1117/12.765195
Show Author Affiliations
S. D. Bergeson, Brigham Young Univ. (United States)
J. B. Peatross, Pharmanex Research Institute (United States)
N. J. Eyring, Pharmanex Research Institute (United States)
J. F. Fralick, Pharmanex Research Institute (United States)
S. B. Ferguson, Pharmanex Research Institute (United States)

Published in SPIE Proceedings Vol. 6853:
Biomedical Optical Spectroscopy
Anita Mahadevan-Jansen; Robert R. Alfano; Alvin Katz; Wolfgang Petrich, Editor(s)

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