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Proceedings Paper

Estimation of absorption coefficient in bottom regions in multi-layered turbid media based on the time-domain depth sensitivity: a Monte Carlo investigation
Author(s): Chie Sato; Miho Shimada; Yoko Hoshi
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Paper Abstract

We attempted to selectively determine the absorption coefficient (μa) of bottom regions in two- and four-layered models with time-domain near infrared measurement. The difference curve in the time-resolved reflectance between a target and a reference medium was divided into segments, and a slope of each segment was calculated to determine depth-dependent μaaseg). The deviation of μaseg in later time segments from the real μa of the bottom layer was μaseg in an earlier time segment to that in a later one. Using this function, we could determine μa in the bottom layer for various target media with different conditions.

Paper Details

Date Published: 22 February 2008
PDF: 8 pages
Proc. SPIE 6864, Biomedical Applications of Light Scattering II, 686413 (22 February 2008); doi: 10.1117/12.764033
Show Author Affiliations
Chie Sato, Tokyo Institute of Psychiatry (Japan)
Miho Shimada, Institute for Molecular Science (Japan)
Yoko Hoshi, Tokyo Institute of Psychiatry (Japan)

Published in SPIE Proceedings Vol. 6864:
Biomedical Applications of Light Scattering II
Adam Wax; Vadim Backman, Editor(s)

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