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Proceedings Paper

A novel method of using hollow-core photonic crystal fiber as a Raman biosensor
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Paper Abstract

A new method for using a non-selectively filled hollow-core photonic crystal fiber (HC-PCF) as a sensitive Raman spectroscopy platform suitable for biosensing applications is presented. A 1550 HC-PCF was completely filled with ethanol (core and cladding holes). Using a 785nm excitation laser, the Raman spectrum of ethanol in the fiber core was obtained and compared with the equivalent Raman spectrum of an ethanolfilled cuvette. Using a relatively short 9.5cm length of HC-PCF, a Raman signal enhancement factor of 40 over a bulk solution of ethanol was observed under the same excitation conditions. The small sample volume utilized and longer interaction length provides the potential for compact, sensitive, and low-power Raman sensing of biological materials

Paper Details

Date Published: 22 February 2008
PDF: 8 pages
Proc. SPIE 6865, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V, 68650E (22 February 2008); doi: 10.1117/12.763158
Show Author Affiliations
Majid Naji, Univ. of Ottawa (Canada)
Altaf Khetani, Univ. of Ottawa (Canada)
Neil Lagali, Ottawa Health Research Institute and The Ottawa Hospital (Canada)
Rejean Munger, Ottawa Health Research Institute and The Ottawa Hospital (Canada)
Hanan Anis, Univ. of Ottawa (Canada)


Published in SPIE Proceedings Vol. 6865:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V
Alexander N. Cartwright; Dan V. Nicolau, Editor(s)

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