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Proceedings Paper

Realtime photoacoustic microscopy of murine cardiovascular and respiratory dynamics in vivo
Author(s): Roger J. Zemp; Liang Song; Rachel Bitton; K. Kirk Shung; Lihong V. Wang
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Paper Abstract

While photoacoustic imaging has emerged as a promising modality in recent years, a key drawback of practical and widespread use of the technique has been slow imaging rates. We present a 30-MHz array-based photoacoustic imaging system that can acquire and display photoacoustic images in realtime. Realtime display is very helpful and provides the system operator the ability to better navigate and position the probe for selecting a desired anatomical field of view. The system is capable of imaging at 50 frames per second to depths of a few mm in tissue. We used this system to successfully image the beating hearts of young athymic nude mice in vivo. Also of interest was the ability to visualize microvascular changes during respiration.

Paper Details

Date Published: 29 February 2008
PDF: 8 pages
Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68560G (29 February 2008); doi: 10.1117/12.763127
Show Author Affiliations
Roger J. Zemp, Washington Univ. in St. Louis (United States)
Liang Song, Washington Univ. in St. Louis (United States)
Rachel Bitton, Univ. of Southern California (United States)
K. Kirk Shung, Univ. of Southern California (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 6856:
Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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