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Proceedings Paper

Microchips fabricated by femtosecond laser micromachining in glass for observation of aquatic microorganisms
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Paper Abstract

We demonstrate the fabrication of three-dimensional (3D) hollow microstructures embedded in photostructurable glass by a nonlinear multiphoton absorption process using a femtosecond (fs) laser. Fs laser direct writing followed by annealing and successive wet etching in dilute hydrofluoric (HF) acid solution resulted in the rapid manufacturing of microchips with 3-D hollow microstructures for the dynamic observation of living microorganisms in fresh water. The embedded microchannel structure enables us to analyze the continuous motion of Euglena gracilis and Dinoflagellate. Such microchips, referred to as nano-aquariums realize the efficient and highly functional observation of microorganisms.

Paper Details

Date Published: 12 February 2008
PDF: 8 pages
Proc. SPIE 6886, Microfluidics, BioMEMS, and Medical Microsystems VI, 68860D (12 February 2008); doi: 10.1117/12.762966
Show Author Affiliations
Y. Hanada, RIKEN--The Institute of Physical and Chemical Research (Japan)
K. Sugioka, RIKEN--The Institute of Physical and Chemical Research (Japan)
H. Kawano, RIKEN Brain Science Institute (Japan)
I. Ishikawa, RIKEN Brain Science Institute (Japan)
A. Miyawaki, RIKEN Brain Science Institute (Japan)
K. Midorikawa, RIKEN--The Institute of Physical and Chemical Research (Japan)


Published in SPIE Proceedings Vol. 6886:
Microfluidics, BioMEMS, and Medical Microsystems VI
Wanjun Wang; Claude Vauchier, Editor(s)

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