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Proceedings Paper

Photodynamic therapy (PDT) to treat a chronic skin wound in a dog
Author(s): Raduan Hage; Hélio Plapler; Renata Andrade Bitar
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Paper Abstract

Photodynamic Therapy (PDT) is an emerging and promising therapeutic modality for treatment of a wide variety of malignant and nononcologic tumors, as well as in the treatment of infected skin ulcers. This study evaluated the effectiveness of the PDT to treat a chronic skin wound that had been already subjected to several clinical and surgical type treatments in a dog. The animal with an infected chronic skin wound with 8 cm diameter in the left leg received an injection of an aqueous solution of 1% methylene blue (MB) with 2% lidocaine into the lesion. After MB injection the wound was irradiated using a LED (LED-VET MMOptics(r)) with a wavelength between 600 and 700 nm, 2 cm diameter circular light beam, of 150 mW of power, light dose of 50 J/cm2. After 3 and 6 weeks PDT was repeated and the wound was re-evaluated. Complete healing was achieved 10 weeks after the first procedure.

Paper Details

Date Published: 11 February 2008
PDF: 6 pages
Proc. SPIE 6845, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVII, 68450X (11 February 2008); doi: 10.1117/12.761679
Show Author Affiliations
Raduan Hage, Univ. Federal de São Paulo (Brazil)
Hélio Plapler, Univ. Federal de São Paulo (Brazil)
Renata Andrade Bitar, Univ. Federal de São Paulo (Brazil)


Published in SPIE Proceedings Vol. 6845:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVII
David Kessel, Editor(s)

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