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Proceedings Paper

Near-infrared fluorescence imaging for colonic cancer detection
Author(s): Xiaozhuo Shao; Jianhua Mo; Wei Zheng; Zhiwei Huang
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Paper Abstract

Near-infrared (NIR) fluorescence imaging is a novel optical technique with an ability of probing larger volume of tissues or lesions located in deep tissue areas. An integrated fluorescence and reflectance imaging system was developed to evaluate its potential for cancer diagnosis. The results show that the NIR autofluorescence intensity of normal colon tissues is significantly higher than that of cancer, and the diagnostic accuracy of 92.8% can be achieved using NIR autofluorescence/reflectance imaging. This work demonstrates that NIR autofluorescence/NIR reflectance imaging technique has potential for colonic cancer diagnosis and detection.

Paper Details

Date Published: 12 February 2008
PDF: 4 pages
Proc. SPIE 6848, Advanced Biomedical and Clinical Diagnostic Systems VI, 68480F (12 February 2008); doi: 10.1117/12.761463
Show Author Affiliations
Xiaozhuo Shao, National Univ. of Singapore (Singapore)
Jianhua Mo, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 6848:
Advanced Biomedical and Clinical Diagnostic Systems VI
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron; Gerald E. Cohn, Editor(s)

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