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Proceedings Paper

Optical coherence computed tomography
Author(s): Li Li; Lihong V. Wang
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Paper Abstract

We proposed a novel time-resolved optical tomography, optical coherence computed tomography. It married the key concepts of time-resolved diffuse optical tomography and optical coherence tomography. Both ballistic and multiple-scattered photons were measured at multiple source-detection positions by low-coherence interferometry. It measures the reemitted light with a temporal resolution of 56 femtoseconds, which is much better than the resolution of conventional time-resolved detection systems. A light-tissue interaction model was established using the time-resolved Monte Carlo method. The optical properties were then reconstructed by solving the inverse time-resolved radiative transport problem under the first Born approximation. Our initial results showed the potential of this technology to bridge the gap between diffuse optical tomography and optical coherence tomography.

Paper Details

Date Published: 6 February 2008
PDF: 8 pages
Proc. SPIE 6855, Complex Dynamics and Fluctuations in Biomedical Photonics V, 68550H (6 February 2008); doi: 10.1117/12.761431
Show Author Affiliations
Li Li, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 6855:
Complex Dynamics and Fluctuations in Biomedical Photonics V
Valery V. Tuchin; Lihong V. Wang, Editor(s)

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