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Proceedings Paper

Imaging of optical scattering contrast using ultrasound-modulated optical tomography
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Paper Abstract

Using a CCD-based speckle contrast detection scheme of ultrasound-modulated optical tomography (UOT), we show the feasibility of imaging objects having different optical scattering coefficients relative to the surrounding scattering medium. Our results show that the spatial resolution depends on the ultrasound parameters and the image contrast depends on the difference in scattering coefficient between the object and the surrounding medium. Experimental measurements are in agreement with Monte Carlo simulations and analytical calculations. This study complements previous UOT experiments that demonstrated optical absorption contrast. It also demonstrates that UOT complements photoacoustic tomography, which is sensitive to optical absorption contrast.

Paper Details

Date Published: 11 March 2008
PDF: 8 pages
Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68561P (11 March 2008); doi: 10.1117/12.761391
Show Author Affiliations
Sri-Rajasekhar Kothapalli, Washington Univ. in St. Louis (United States)
Sava Sakadžić, Massachusetts General Hospital and Harvard Medical School (United States)
Chulhong Kim, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 6856:
Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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