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Proceedings Paper

Porcine skin ED50 damage thresholds for 1214 nm laser irradiation
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Paper Abstract

A series of experiments were conducted in vivo on porcine skin to determine the ED50 damage thresholds for 1214 nm continuous wave laser irradiation. These results provide new information for refinement of Maximum Permissible Exposure (MPE). The study employed exposure durations of 1 sec, 3 sec, and 10 seconds with nominal spot diameters of 6 mm, 8 mm and 10 mm and as a function of laser power. The effect of each irradiation was evaluated acutely, one hour after exposure, and 24 hours post exposure. Probit analysis was conducted to estimate the dose for 50% probability of laser-induced damage (ED50); Damage was defined as persistent redness at the site of irradiation for the pig skin after 24 hours. The results indicated that Maximum Permissible Exposure (MPE) limits should be lowered for the laser beam diameters larger than 6 mm.

Paper Details

Date Published: 20 February 2008
PDF: 8 pages
Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 685406 (20 February 2008); doi: 10.1117/12.761380
Show Author Affiliations
Bo Chen, The Univ. of Texas at Austin (United States)
Jeffrey Oliver, Air Force Research Lab. (United States)
Rebecca Vincelette, The Univ. of Texas at Austin (United States)
Ginger Pocock, The Univ. of Texas at Austin (United States)
Raiyan Zaman, The Univ. of Texas at Austin (United States)
Ashley J. Welch, The Univ. of Texas at Austin (United States)


Published in SPIE Proceedings Vol. 6854:
Optical Interactions with Tissue and Cells XIX
Steven L. Jacques; William P. Roach; Robert J. Thomas, Editor(s)

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