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Proceedings Paper

Segmentation of the retinal pigment epithelium by polarization sensitive optical coherence tomography
Author(s): Christoph K. Hitzenberger; Erich Götzinger; Michael Pircher; Bernhard Baumann; Stephan Michels; Wolfgang Geitzenauer; Ursula Schmidt-Erfurth
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Paper Abstract

We report on a new method for segmenting the retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous segmentation algorithms that were based on variations of backscattered intensity between individual layers, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy eyes and in eyes of patients with age related macular degeneration.

Paper Details

Date Published: 5 March 2008
PDF: 4 pages
Proc. SPIE 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, 684705 (5 March 2008); doi: 10.1117/12.761177
Show Author Affiliations
Christoph K. Hitzenberger, Medical Univ. of Vienna (Austria)
Erich Götzinger, Medical Univ. of Vienna (Austria)
Michael Pircher, Medical Univ. of Vienna (Austria)
Bernhard Baumann, Medical Univ. of Vienna (Austria)
Stephan Michels, General Hospital and Medical Univ. of Vienna (Austria)
Wolfgang Geitzenauer, General Hospital and Medical Univ. of Vienna (Austria)
Ursula Schmidt-Erfurth, General Hospital and Medical Univ. of Vienna (Austria)


Published in SPIE Proceedings Vol. 6847:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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