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Proceedings Paper

Threshold parameters of the mechanisms of selective nanophotothermolysis with gold nanoparticles
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Paper Abstract

Photothermal-based effects in and around gold nanoparticles under action of short (nano, pico- and femtosecond) laser pulses are analyzed with focus on photoacoustic effects due to the thermal expansion of nanoparticles and liquid around them, thermal protein denaturation, explosive liquid vaporization, melting and evaporation of nanoparticle, optical breakdown initiated by nanoparticles and accompanied to shock waves and explosion (fragmentation) of gold nanoparticles. Characteristic parameters for these processes such as the temperature and laser intensity thresholds are summarized to provide basis for comparison of different mechanisms of selective nanophotothermolysis of different targets (e.g., cancer cells, bacteria, viruses, fungi, and helminths).

Paper Details

Date Published: 20 February 2008
PDF: 10 pages
Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 685412 (20 February 2008); doi: 10.1117/12.759060
Show Author Affiliations
Victor Pustovalov, Belarusian Institute of System Analysis (Belarus)
Vladimir Zharov, Univ. of Arkansas for Medical Sciences (United States)


Published in SPIE Proceedings Vol. 6854:
Optical Interactions with Tissue and Cells XIX
Steven L. Jacques; William P. Roach; Robert J. Thomas, Editor(s)

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