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Proceedings Paper

Novel fiber-optic probe design for depth-resolved fluorescence measurements: Monte Carlo simulations
Author(s): Franck Jaillon; Wei Zheng; Zhiwei Huang
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Paper Abstract

Fluorescence spectroscopy diagnostics on epithelium tissues requires being able to obtain depth resolved measurements. We study here an optical probe combining a ball lens, a flat tip excitation fiber and a bevel collection fiber. Varying the angle of the bevel collection fiber is seen to be a way of changing the depth of the fluorescence collected signal. Fixing the excitation-collection distance, we observe that large bevel angles of the collection fiber tip allows to augment the fluorescence collected signal of the stroma, whereas small angles improve the signal from the epithelial layer.

Paper Details

Date Published: 19 November 2007
PDF: 6 pages
Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 68261D (19 November 2007); doi: 10.1117/12.755262
Show Author Affiliations
Franck Jaillon, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 6826:
Optics in Health Care and Biomedical Optics III
Xingde Li; Qingming Luo; Ying Gu, Editor(s)

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