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Proceedings Paper

Label-free detection of chemical messenger proteins
Author(s): Andrea M. Armani; Scott E. Fraser; Kerry J. Vahala
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Paper Abstract

Recently, quality factors greater than 100 million were demonstrated using planar arrays of silica microtoroid resonators. These high Q factors allow the toroidal resonators to perform very sensitive detection experiments. By functionalizing the silica surface of the toroid using antibodies, the toroidal resonators become both specific and sensitive detectors. Targeted detection of Interleukin-2, a cytokine which stimulates production of T cells, is demonstrated. Additional cross-reactivity experiments are also performed to verify the sensor's behavior in a more complex environment.

Paper Details

Date Published: 15 September 2007
PDF: 9 pages
Proc. SPIE 6717, Optomechatronic Micro/Nano Devices and Components III, 67170D (15 September 2007); doi: 10.1117/12.754339
Show Author Affiliations
Andrea M. Armani, California Institute of Technology (United States)
Scott E. Fraser, California Institute of Technology (United States)
Kerry J. Vahala, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 6717:
Optomechatronic Micro/Nano Devices and Components III

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