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Proceedings Paper

Influence of laser irradiation on superoxide dismutase activity of human lymphocytes in vitro
Author(s): Nataly M. Kozlova; Anna N. Antonovich; Ekaterina I. Slobozhanina
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Paper Abstract

The treatment of blood with low intensity laser irradiation has become popular in a variety of clinical applications due to its anti-inflammatory, biostimulative and immune-stimulatory effects etc. Laser blood irradiation with infrared and red laser sources have the potential for stimulating antioxidant enzymes activities. At present study the influence of red and infra-red laser irradiation at different doses on superoxide dismutase (SOD) activity of peripheral blood lymphocytes was investigated in vitro. Suspensions of human lymphocytes (concentration of cells 1x106 cells/ml) were irradiated with red (670 nm) and infrared (980 nm) therapy lasers at different light doses (0-600 J/sample) and light power (4,5 and 15 mW for red; 50 and 500 mW for infrared) at 20°C. It is revealed doze-depended effect of red and infra-red laser irradiation on superoxide dismutaze activity of peripheral blood lymphocytes. The SOD activity, first of all, depends on irradiation time, but not on intensity or wavelength of irradiation. These data can explain the positive medical effects of a laser blood irradiation. The obtained results confirm a hypothesis that laser irradiation with the different wavelength characteristic (red and infra-red light ranges) reveals a stimulating effect on SOD - antioxidant defence system enzyme in peripheral blood lymphocytes.

Paper Details

Date Published: 1 August 2007
PDF: 4 pages
Proc. SPIE 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine, 67341R (1 August 2007); doi: 10.1117/12.753428
Show Author Affiliations
Nataly M. Kozlova, Institute of Biophysics and Cell Engineering (Belarus)
Anna N. Antonovich, Institute of Biophysics and Cell Engineering (Belarus)
Ekaterina I. Slobozhanina, Institute of Biophysics and Cell Engineering (Belarus)


Published in SPIE Proceedings Vol. 6734:
International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine

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