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Proceedings Paper

Prostate cancer detection by laser induced autofluorescence and multicomponent spectroscopy
Author(s): Georg Salomon; Thorsten Hess; Andreas Erbersdobler; Christian Eichelberg; Siegfried Greschner; Andrey N. Sobchuk; Anna K. Korolik; Nicolai A. Nemkovich; Jürgen Schreiber; Martin Herms; Markus Graefen; Hartwig Huland
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Paper Abstract

Laser-Induced-Autofluorescence (LIAF), White-Light-Remission (WLR) and Electrical-Impedance-Measurement (EIM) in combination with principal component analysis were used at first time for differentiation benign from malignant prostatic tissue in vitro. The used complex statistical processing of the data has shown a differentiation of benign and malignant prostatic tissue with a sensitivity of 93.8% and a specificity of 92.4%.

Paper Details

Date Published: 1 August 2007
PDF: 8 pages
Proc. SPIE 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine, 67340H (1 August 2007); doi: 10.1117/12.753209
Show Author Affiliations
Georg Salomon, Univ. Hospital Hamburg-Eppendorf (Germany)
Thorsten Hess, Univ. Hospital Hamburg-Eppendorf (Germany)
Andreas Erbersdobler, Univ. Hospital Hamburg-Eppendorf (Germany)
Christian Eichelberg, Univ. Hospital Hamburg-Eppendorf (Germany)
Siegfried Greschner, Fraunhofer Institute for Nondestructive Testing (Germany)
Andrey N. Sobchuk, B.I. Stepanov Institute of Physics (Belarus)
Anna K. Korolik, Belorussian State Medical Univ. (Belarus)
Nicolai A. Nemkovich, B.I. Stepanov Institute of Physics (Belarus)
Jürgen Schreiber, Fraunhofer Institute for Nondestructive Testing (Germany)
Martin Herms, Fraunhofer Institute for Nondestructive Testing (Germany)
Markus Graefen, Martini Clinic, Prostate Cancer Ctr. (Germany)
Hartwig Huland, Univ. Hospital Hamburg-Eppendorf (Germany)
Martini Clinic, Prostate Cancer Ctr. (Germany)


Published in SPIE Proceedings Vol. 6734:
International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine

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