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Proceedings Paper

Conformation change of enzyme molecules in laser radiation field
Author(s): N. S. Leshenyuk; M. V. Prigun; E. E. Apanasevitsh; G. S. Kruglik
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Paper Abstract

As a result of an analysis of macromolecules properties in the coherent optical radiation field and with allowance for the experimentally obtained unique data on the interaction of lazer radiation with biomolecules (dependence of the interaction efficiency on the coherence length, presence of the effect in the spectra region far from the absorption band), a mechanism of wave interaction is developed. Using this mathematical model, the calculations of a change in the macromolecules oscillatory energy in the coherent radiation field are performed. It is shown that the increase of macromolecules oscillatory energy depends strongly on the coherence length of radiation. On exposure to noncoherent radiation, the biomolecules oscillatory energy practically does not change, whereas on exposure to laser radiation (coherence length ≈3 cm), energy of oscillations of atoms increases by an order of 2÷4, which results in a change in the conformation of biomolecules and activity of enzymes. Recently a lot of data are received concerning the change of lysosomal enzymes activity in blood plasma under action of laser radiation.

Paper Details

Date Published: 9 July 2007
PDF: 9 pages
Proc. SPIE 6727, ICONO 2007: Nonlinear Laser Spectroscopy and High-Precision Measurements; and Fundamentals of Laser Chemistry and Biophotonics, 672727 (9 July 2007); doi: 10.1117/12.752458
Show Author Affiliations
N. S. Leshenyuk, International Sakharov Environmental Univ. (Belarus)
M. V. Prigun, International Sakharov Environmental Univ. (Belarus)
E. E. Apanasevitsh, International Sakharov Environmental Univ. (Belarus)
G. S. Kruglik, Belarusian National Technical Univ. (Belarus)


Published in SPIE Proceedings Vol. 6727:
ICONO 2007: Nonlinear Laser Spectroscopy and High-Precision Measurements; and Fundamentals of Laser Chemistry and Biophotonics

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