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Proceedings Paper

Light-microscopic image restoration via edge detection
Author(s): Mingzhu Sun; Xin Zhao; Guizhang Lu
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Paper Abstract

A semi-blind image restoration approach is put forward in this paper for light-microscopy system. Microscope creates unavoidable light artefacts because of the Point Spread Function (PSF) of the optical system, and our early research shows that PSF of the microscopy system can be modeled as isotropic Gaussian blur. That is the motivation of this paper. We present an algorithm, based on functional minimization, which integrates Canny edge detection with semi-blind deconvolution. An alternating minimization (AM) implicit iterative scheme is devised to recover the image and simultaneously identify PSF. Good performance is observed with numerically blurred images and really microscopic images, even under the presence of high noise level.

Paper Details

Date Published: 15 November 2007
PDF: 9 pages
Proc. SPIE 6786, MIPPR 2007: Automatic Target Recognition and Image Analysis; and Multispectral Image Acquisition, 67860V (15 November 2007); doi: 10.1117/12.748919
Show Author Affiliations
Mingzhu Sun, Nankai Univ. (China)
Xin Zhao, Nankai Univ. (China)
Guizhang Lu, Nankai Univ. (China)


Published in SPIE Proceedings Vol. 6786:
MIPPR 2007: Automatic Target Recognition and Image Analysis; and Multispectral Image Acquisition
Tianxu Zhang; Tianxu Zhang; Carl Anthony Nardell; Carl Anthony Nardell; Hanqing Lu; Duane D. Smith; Hangqing Lu, Editor(s)

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