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Proceedings Paper

Assessment of diffusion coefficient of glycerol into the skin ex vivo
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Paper Abstract

In present study we have considered diffusion of immersion agent into the skin through thermally pretreated stratum corneum solving the corresponding diffusion problem. Algorithm of refractive index of interstitial liquid and diffusion coefficient of immersion agent into biotissue estimations at a creation of lattice-like pattern of localized thermal damage islets in the stratum corneum, was develop. Theoretical model which sufficiently describes the influence of immersion agents on skin optical properties was presented. The diffusion coefficient of glycerol into pig skin ex vivo at creating a lattice of islets of damage in the stratum corneum is 0.84±0.08 μm2/s.

Paper Details

Date Published: 1 May 2007
PDF: 9 pages
Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65343J (1 May 2007); doi: 10.1117/12.741500
Show Author Affiliations
Anna A. Gavrilova, Saratov State Univ. (Russia)
Alexander B. Pravdin, Saratov State Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. (Russia)
Gregory B. Altshuler, Palomar Medical Technologies, Inc. (United States)
Ilya V. Yaroslavsky, Palomar Medical Technologies, Inc. (United States)


Published in SPIE Proceedings Vol. 6534:
Fifth International Conference on Photonics and Imaging in Biology and Medicine

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