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Proceedings Paper

Linear and nonlinear laser-trapping microrheology
Author(s): D. Mizuno
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Paper Abstract

We have developed a high-bandwidth technique for active 2-particle microrheology (AMR) with which we can probe linear and nonlinear responses of soft materials. Micron-sized colloidal probe particles are driven by an oscillating optical trap, and the resulting correlated motions of neighboring particles are detected by laser interferometry. Lock-in detection at the driving frequency and at its second harmonic makes it possible to measure the linear and the non-linear response of the embedding medium at the same time. We demonstrate the sensitivity of the method by detecting a second-harmonic response in water which is of purely geometric origin and which can be fully understood within linear hydrodynamics.

Paper Details

Date Published: 5 September 2007
PDF: 11 pages
Proc. SPIE 6644, Optical Trapping and Optical Micromanipulation IV, 66440L (5 September 2007); doi: 10.1117/12.739441
Show Author Affiliations
D. Mizuno, Kyushu Univ. (Japan)


Published in SPIE Proceedings Vol. 6644:
Optical Trapping and Optical Micromanipulation IV
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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