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Proceedings Paper

Micro-optics for optical trapping in microfluidics
Author(s): Fabrice Merenda; Johann Rohner; Elodie Lamothe; Pedro Pascoal; Jean-Marc Fournier; René-Paul Salathé
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Paper Abstract

Micro-optical components offer several possibilities for creating large matrices of optical traps, either when working on inverted microscopes, or by directly integrating miniaturized optical components at the level of a micro-fluidic chip. In this article we focus on two particular configurations, both allowing to generate large arrays of 3D optical traps. The first configuration takes advantage of an array of refractive microlenses to generate multiple optical tweezers within the focal plane of a high-NA microscope objective. The second configuration relies on an array of focusing high-NA micromirrors which are directly integrated at the level of a micro-fluidic chip. We also present measurements of the maximal optical trapping forces that can be reached with several types of cells commonly employed in biology and biotechnology, and demonstrate that these forces are essentially related to the bulk refractive index of the cells.

Paper Details

Date Published: 5 September 2007
PDF: 10 pages
Proc. SPIE 6644, Optical Trapping and Optical Micromanipulation IV, 66440P (5 September 2007); doi: 10.1117/12.738268
Show Author Affiliations
Fabrice Merenda, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Johann Rohner, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Elodie Lamothe, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Pedro Pascoal, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Jean-Marc Fournier, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
René-Paul Salathé, Ecole Polytechnique Fédérale de Lausanne (Switzerland)


Published in SPIE Proceedings Vol. 6644:
Optical Trapping and Optical Micromanipulation IV
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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