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Proceedings Paper

Pancreatic tissue assessment using fluorescence and reflectance spectroscopy
Author(s): Malavika Chandra; David Heidt; Diane Simeone; Barbara McKenna; James Scheiman; Mary-Ann Mycek
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Paper Abstract

The ability of multi-modal optical spectroscopy to detect signals from pancreatic tissue was demonstrated by studying human pancreatic cancer xenografts in mice and freshly excised human pancreatic tumor tissue. Measured optical spectra and fluorescence decays were correlated with tissue morphological and biochemical properties. The measured spectral features and decay times correlated well with expected pathological differences in normal, pancreatitis and adenocarcinoma tissue states. The observed differences between the fluorescence and reflectance properties of normal, pancreatitis and adenocarcinoma tissue indicate a possible application of multi-modal optical spectroscopy to differentiating between the three tissue classifications.

Paper Details

Date Published: 11 July 2007
PDF: 8 pages
Proc. SPIE 6628, Diagnostic Optical Spectroscopy in Biomedicine IV, 66281R (11 July 2007); doi: 10.1117/12.729519
Show Author Affiliations
Malavika Chandra, Univ. of Michigan (United States)
David Heidt, Univ. of Michigan Medical School (United States)
Diane Simeone, Univ. of Michigan Medical School (United States)
Barbara McKenna, Univ. of Michigan Medical School (United States)
James Scheiman, Univ. of Michigan Medical School (United States)
Mary-Ann Mycek, Univ. of Michigan (United States)
Univ. of Michigan Medical School (United States)


Published in SPIE Proceedings Vol. 6628:
Diagnostic Optical Spectroscopy in Biomedicine IV
Dietrich Schweitzer; Maryann Fitzmaurice, Editor(s)

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