Share Email Print

Proceedings Paper

Semi-analytical method for rapid calculation of time-resolved reflectance from bi-layered tissue models
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Photon transport in complex biological tissues is most accurately predicted via Monte Carlo (MC) modeling methods, which often require lengthy computation times. In this report, a semi-analytical technique (henceforth referred to as PI-scaling) was derived that combines MC simulation, absorption scaling, and path integrals (PI) to rapidly reconstruct time-resolved reflectance from the surface of bilayered epithelial tissue models. Comparisons to forward MC simulations indicated that the PI−scaling method was accurate to better than 10% for tissue models where the optical properties of the top layer did not greatly influence the time-resolved reflectance. Employing such a method should provide a novel solution to the first step of the problem of rapid simulation of time-resolved reflectance of photons in layered tissues.

Paper Details

Date Published: 19 July 2007
PDF: 10 pages
Proc. SPIE 6628, Diagnostic Optical Spectroscopy in Biomedicine IV, 66280W (19 July 2007); doi: 10.1117/12.729431
Show Author Affiliations
Robert H. Wilson, Univ. of Michigan (United States)
Karthik Vishwanath, Duke Univ. (United States)
Mary-Ann Mycek, Univ. of Michigan (United States)

Published in SPIE Proceedings Vol. 6628:
Diagnostic Optical Spectroscopy in Biomedicine IV
Dietrich Schweitzer; Maryann Fitzmaurice, Editor(s)

© SPIE. Terms of Use
Back to Top