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Proceedings Paper

Transmission RF diffuse optical tomography instrument for human breast imaging
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Paper Abstract

In this paper, we describe a novel clinical breast diffuse optical tomography (DOT) instrument for CW and RF data acquisition in transmission geometry. It is designed to be able to acquire a massive amount of data in a short amount of time available for patient measurement by using a 209-channel galvo-based fast optical switch and a fast electron-multiplying CCD. In addition to CW measurements, RF measurements were made by using an electro-optic modulator for source modulation and a gain-modulated image intensifier for detection. The patient bed has many clinically-oriented features as well as improved data acquisition rate and transmission RF measurement capability. A series of preliminary results will be shown, including a heterodyne RF experiment for bulk property measurement and a CW experiment for 3D imaging. In order to deal with large data size, a linear reconstruction algorithm that exploits separability of the inverse problem in Fourier domain is used for fast and memory-load-free reconstruction.

Paper Details

Date Published: 12 July 2007
PDF: 6 pages
Proc. SPIE 6629, Diffuse Optical Imaging of Tissue, 66291R (12 July 2007); doi: 10.1117/12.728623
Show Author Affiliations
Kijoon Lee, Univ. of Pennsylvania (United States)
Soren D. Konecky, Univ. of Pennsylvania (United States)
Regine Choe, Univ. of Pennsylvania (United States)
Han Y. Ban, Univ. of Pennsylvania (United States)
Alper Corlu, Univ. of Pennsylvania (United States)
Turgut Durduran, Univ. of Pennsylvania (United States)
Arjun G. Yodh, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 6629:
Diffuse Optical Imaging of Tissue
Brian W. Pogue; Rinaldo Cubeddu, Editor(s)

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