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Proceedings Paper

System integration and development for biological warfare agent surveillance
Author(s): Jacob A. Mark; Lance D. Green; Alina Deshpande; P. Scott White
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Paper Abstract

A wide variety of technical needs exist for surveillance, monitoring, identifying, or detecting pathogens with potential use as biological terrorism or warfare agents. Because the needs vary greatly among diverse applications, tailored systems are needed that meet performance, information, and cost requirements. A systems perspective allows developers to identify chokepoints for each application, and focus R&D investments on the limiting factors. Surveillance and detection systems are comprised of three primary components: information (markers), chemistries (assays), and instrumentation for "readout". Careful consideration of these components within the context of each application will allow for increases in efficiency and performance not generally realized when researchers focus on a single component in isolation. In fact, many application requirements can be met with simple novel combinations of existing technologies, without the need for huge investments in basic research. Here we discuss some of the key parameters for surveillance, detection, and identification of biothreat agents, and provide examples of focused development that addresses key bottlenecks, and greatly improve system performance.

Paper Details

Date Published: 4 May 2007
PDF: 12 pages
Proc. SPIE 6540, Optics and Photonics in Global Homeland Security III, 65401D (4 May 2007); doi: 10.1117/12.722553
Show Author Affiliations
Jacob A. Mark, Los Alamos National Lab. (United States)
Lance D. Green, Los Alamos National Lab. (United States)
Alina Deshpande, Los Alamos National Lab. (United States)
P. Scott White, Los Alamos National Lab. (United States)

Published in SPIE Proceedings Vol. 6540:
Optics and Photonics in Global Homeland Security III
Theodore T. Saito; Daniel Lehrfeld; Michael J. DeWeert, Editor(s)

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