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Proceedings Paper

Fundamentals and developments of biological tissue optical clearing
Author(s): Jingying Jiang; Kexin Xu
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Paper Abstract

This talk reviews the state ofthe art of tissue optical clearing techniques in biomedical optics. Following an analysis of the fundamentals of tissue optical clearing, the techniques of tissue optical clearing, especially by the use of biocompatible hyperosmotic agents onto biological tissue, are introduced. The review concludes that under the consideration of clinical safety issue and optical application, the optical clearing by using hyperosmotically active agents would be optimal method to enhance the light penetration depth and improve the imaging contrast, finally facilitate the application of light-based optical diagnostic and therapeutic techniques.

Paper Details

Date Published: 27 October 2006
PDF: 6 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604744 (27 October 2006); doi: 10.1117/12.710978
Show Author Affiliations
Jingying Jiang, Tianjin Univ. (China)
Kexin Xu, Tianjin Univ. (China)


Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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