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Proceedings Paper

Wide microfluidic channel used in suspension biochip detection system
Author(s): Guoxiong Xu; Xi Zhang; Xuxiang Ni; Zukang Lu; Xiangqun Cao
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Paper Abstract

In this paper we describe a new kind of micro fluidic channel used in suspension biochip detection system suitable to area test of the sample that is different from cytometry, which has been fabricated by us. Cytometry is a conventional platform used in suspension biochip technology. At first, our detection system employs a widen micro fluidic channel width of lmm and different depth 50μ, 1OOμ,which is suitable to different size sample flow in the channel instead of the thin pipe used in the cytometry. Secondly suspension array is analyzed by CCD imaging technology in parallel in stead of detection micro beads or protein one by one. The wide micro channels have been fabricated by three ways: laser ablation, chemical etching and mechanical method. The stability of the micro field is a key factor of the biochip detection system when sample flows through the wide micro channel. A novel sample control method to keep the suspension microspheres flow stably throw the test area has been presented.

Paper Details

Date Published: 27 October 2006
PDF: 6 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604733 (27 October 2006); doi: 10.1117/12.710920
Show Author Affiliations
Guoxiong Xu, Zhejiang Univ. (China)
Anhui Univ. of Technology (China)
Xi Zhang, Zhejiang Univ. (China)
Xuxiang Ni, Zhejiang Univ. (China)
Zukang Lu, Zhejiang Univ. (China)
Xiangqun Cao, Zhejiang Univ. (China)


Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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