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Proceedings Paper

Advanced time-correlated single photon counting technique for spectroscopy and imaging of biological systems
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Paper Abstract

We present a multi-dimensional TCSPC technique that simultaneously records the photon distribution over the time in the fluorescence decay, the wavelength, and the coordinates of a two-dimensional scan or the time since the start of the experiment. We demonstrate the application of the technique to diffuse optical tomography, single-point autofluorescence measurements of skin, and multi-spectra autofluorescence lifetime imaging of tissue.

Paper Details

Date Published: 27 October 2006
PDF: 5 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604714 (27 October 2006); doi: 10.1117/12.710872
Show Author Affiliations
Wolfgang Becker, Becker & Hickl GmbH (Germany)
Axel Bergmann, Becker & Hickl GmbH (Germany)
Michal Kacprzak, Institute of Biocybernetics and Biomedical Engineering (Poland)
Adam Liebert, Institute of Biocybernetics and Biomedical Engineering (Poland)


Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine

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