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Proceedings Paper

Photobiomodulation on senescence
Author(s): Timon Cheng-Yi Liu; Lei Cheng; Dong-Liang Rong; Xiao-Yang Xu; Li-Ping Cui; Jian Lu; Xiao-Yuan Deng; Song-Hao Liu
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Paper Abstract

Photobiomodulation (PBM) is an effect oflow intensity monochromatic light or laser irradiation (LIL) on biological systems. which stimulates or inhibits biological functions but does not result in irreducible damage. It has been observed that PBM can suppress cellular senescence, reverse skin photoageing and improve fibromyalgia. In this paper, the biological information model of photobiomodulation (BIMP) is used to discuss its mechanism. Cellular senescence can result from short, dysfunctional telomeres, oxidative stress, or oncogene expression, and may contribute to aging so that it can be seen as a decline of cellular function in which cAMP plays an important role, which provide a foundation for PBM on senescence since cellular senescence is a reasonable model of senescence and PBM is a cellular rehabilitation in which cAMP also plays an important role according to BIMP. The PBM in reversing skin photoageing and improving fibromyalgia are then discussed in detail.

Paper Details

Date Published: 27 October 2006
PDF: 8 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604732 (27 October 2006); doi: 10.1117/12.710692
Show Author Affiliations
Timon Cheng-Yi Liu, South China Normal Univ. (China)
Lei Cheng, South China Normal Univ. (China)
Dong-Liang Rong, South China Normal Univ. (China)
Xiao-Yang Xu, South China Normal Univ. (China)
Li-Ping Cui, South China Normal Univ. (China)
Jian Lu, Guangzhou Institute of Physical Education (China)
Xiao-Yuan Deng, South China Normal Univ. (China)
Song-Hao Liu, Lab. of Laser Sports Medicine, South China Normal Univ. (China)


Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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