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Proceedings Paper

In-vitro investigations of nanoparticle magnetic thermotherapy: adjuvant effects and comparison to conventional heating
Author(s): Z. Pierce; R. Strawbridge; C. Gaito; L. Dulatas; J. Tate; J. Ogden; P. J. Hoopes
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Paper Abstract

Thermotherapy, particularly magnetic nanoparticle hyperthermia, is a promising modality both as a direct cancer cell killing and as a radiosensitization technique for adjuvant therapy. Dextran-coated iron oxide nanoparticles were mixed with multiple tumor cell lines in solution and exposed to varying magnetic field regimes and combined with traditional external radiotherapy. Heating of cell lines by water bath in temperature patterns comparable to those achieved by nanoparticle hyperthermia was conducted to assess the relative value of nano-magnetic thermotherapy compared with conventional bulk heating techniques and data.

Paper Details

Date Published: 9 February 2007
PDF: 6 pages
Proc. SPIE 6440, Thermal Treatment of Tissue: Energy Delivery and Assessment IV, 64400J (9 February 2007); doi: 10.1117/12.710579
Show Author Affiliations
Z. Pierce, Dartmouth College and Dartmouth Medical School (United States)
R. Strawbridge, Dartmouth College and Dartmouth Medical School (United States)
C. Gaito, Dartmouth College and Dartmouth Medical School (United States)
L. Dulatas, Dartmouth College and Dartmouth Medical School (United States)
J. Tate, Dartmouth College and Dartmouth Medical School (United States)
J. Ogden, Dartmouth College and Dartmouth Medical School (United States)
P. J. Hoopes, Dartmouth College and Dartmouth Medical School (United States)


Published in SPIE Proceedings Vol. 6440:
Thermal Treatment of Tissue: Energy Delivery and Assessment IV
Thomas P. Ryan, Editor(s)

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