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Proceedings Paper

Evaluation of Brownian warps for shape alignment
Author(s): Mads Nielsen
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Paper Abstract

Many methods are used for warping images to non-rigidly register shapes and objects in between medical images in inter- and intra-patient studies. In landmark-based registration linear methods like thin-plate- or b-splines are often used. These linear methods suffer from a number of theoretical deficiencies: they may break or tear apart the shapes, they are not source-destination symmetric, and may not be invertible. Theoretically more satisfactory models using diffeomorphic approaches like "Large Deformations" and "Brownian warps" have earlier proved (in theory and practice) to remove these deficiencies. In this paper we show that the maximum-likelihood Brownian Warps also generalize better in the case of matching fractured vertebrae to normal vertebrae. X-rays of 10 fractured and 1 normal vertebrae have been annotated by a trained radiologist by 6 so-called height points used for fracture scoring, and by the full boundary. The fractured vertebrae have been registered to the normal vertebra using only the 6 height points as landmarks. After registration the Hausdorff distance between the boundaries is measured. The registrations based on Brownian warps show a significantly lower distance to the original boundary.

Paper Details

Date Published: 7 March 2007
PDF: 9 pages
Proc. SPIE 6512, Medical Imaging 2007: Image Processing, 65123Y (7 March 2007); doi: 10.1117/12.710105
Show Author Affiliations
Mads Nielsen, Univ. of Copenhagen (Denmark)
Nordic Bioscience A/S (Denmark)

Published in SPIE Proceedings Vol. 6512:
Medical Imaging 2007: Image Processing
Josien P. W. Pluim; Joseph M. Reinhardt, Editor(s)

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