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Proceedings Paper

Automatic differentiation of melanoma and Clark nevus skin lesions
Author(s): R. W. LeAnder; A. Kasture; A. Pandey; S. E. Umbaugh
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Paper Abstract

Skin cancer is the most common form of cancer in the United States. Although melanoma accounts for just 11% of all types of skin cancer, it is responsible for most of the deaths, claiming more than 7910 lives annually. Melanoma is visually difficult for clinicians to differentiate from Clark nevus lesions which are benign. The application of pattern recognition techniques to these lesions may be useful as an educational tool for teaching physicians to differentiate lesions, as well as for contributing information about the essential optical characteristics that identify them. Purpose: This study sought to find the most effective features to extract from melanoma, melanoma in situ and Clark nevus lesions, and to find the most effective pattern-classification criteria and algorithms for differentiating those lesions, using the Computer Vision and Image Processing Tools (CVIPtools) software package. Methods: Due to changes in ambient lighting during the photographic process, color differences between images can occur. These differences were minimized by capturing dermoscopic images instead of photographic images. Differences in skin color between patients were minimized via image color normalization, by converting original color images to relative-color images. Relative-color images also helped minimize changes in color that occur due to changes in the photographic and digitization processes. Tumors in the relative-color images were segmented and morphologically filtered. Filtered, relative-color, tumor features were then extracted and various pattern-classification schemes were applied. Results: Experimentation resulted in four useful pattern classification methods, the best of which was an overall classification rate of 100% for melanoma and melanoma in situ (grouped) and 60% for Clark nevus. Conclusion: Melanoma and melanoma in situ have feature parameters and feature values that are similar enough to be considered one class of tumor that significantly differs from Clark nevus. Consequently, grouping melanoma and melanoma in situ together achieves the best results in classifying and automatically differentiating melanoma from Clark nevus lesions.

Paper Details

Date Published: 30 March 2007
PDF: 12 pages
Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65142V (30 March 2007); doi: 10.1117/12.709986
Show Author Affiliations
R. W. LeAnder, Southern Illinois Univ., Edwardsville (United States)
A. Kasture, Southern Illinois Univ., Edwardsville (United States)
A. Pandey, Southern Illinois Univ., Edwardsville (United States)
S. E. Umbaugh, Southern Illinois Univ., Edwardsville (United States)

Published in SPIE Proceedings Vol. 6514:
Medical Imaging 2007: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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