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Proceedings Paper

Photoacoustic imaging with focused ultrasonic probe beam
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Paper Abstract

This paper presents a novel model of photoacoustic tomography with an ultrasonic probe beam. A strict theory describes the nonlinear interaction between photoacoustic wave and ultrasonic probe beam. When a pulse laser irradiates on biological tissues, the laser energy will be absorbed by the identity molecule of the tissues, and be converted into heat. Subsequently, the thermal expansion of the instantaneously heated tissues induces photoacoustic waves. So the density, temperature and compressibility of the absorption area will be changed. A focus ultrasonic probe beam with a single frequency passes through the irradiated area, the changes of the properties of the irradiated medium will be coupled with the ultrasonic probe beam, which will propagate through the medium with minimal distortion and can be detected at the surface of the medium. The PA signal in situ can be obtained by demodulating the detected ultrasonic beam. It will take out much more information from the interaction area, which can reflect not only the intrinsic optical properties but also the mechanical and acoustical properties of the tissue. In our experimentation, a Q-switched Nd: YAG pulse laser operated at 1064nm was employed to generate photoacoustic signal, the frequency of ultrasonic probe beam is l0M. By demodulating the detected ultrasonic beam, we obtained very high quality tomography images. So it will provide a new promising method for tumour detection and noninvasion function imaging.

Paper Details

Date Published: 27 October 2006
PDF: 6 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60470H (27 October 2006); doi: 10.1117/12.709928
Show Author Affiliations
Liangzhong Xiang, South China Normal Univ. (China)
Huaimin Gu, South China Normal Univ. (China)

Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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