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Proceedings Paper

Mathematical modeling of dynamic laser coagulation during laser-induced interstitial thermotherapy
Author(s): S. C. Jiang; X. X. Zhang
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Paper Abstract

To describe the complex nonlinear process of laser tissue interactions during laser-induced interstitial thermotherapy (LITT), a two-dimensional mathematical model considering the dynamic changes in the physical tissue properties was developed. A modified Monte Carlo method was developed to simulate photon transport in tissue with a non-uniform optical property field, the finite volume method was used to numerically solve the Pennes bioheat equation to calculate the temperature distribution and the Arrhenius equation was used to predict the thennal damage extent. A temperature control heating method was also incorporated into present model to simulate the LITT clinical treatment to increase thermal damage volume and avoid evaporation and carbonization. The numerical results showed that the dynamic changes in the optical properties, the thermal properties and the blood perfusion rate significanfly affected the damage volume accumulation in tissue and should be included in munerical simulations of the LITT treatment.

Paper Details

Date Published: 27 October 2006
PDF: 7 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604709 (27 October 2006); doi: 10.1117/12.709824
Show Author Affiliations
S. C. Jiang, Tsinghua Univ. (China)
X. X. Zhang, Tsinghua Univ. (China)


Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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