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Proceedings Paper

CAD scheme to detect hemorrhages and exudates in ocular fundus images
Author(s): Yuji Hatanaka; Toshiaki Nakagawa; Yoshinori Hayashi; Yutaka Mizukusa; Akihiro Fujita; Masakatsu Kakogawa; Kazuhide Kawase; Takeshi Hara; Hiroshi Fujita
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Paper Abstract

This paper describes a method for detecting hemorrhages and exudates in ocular fundus images. The detection of hemorrhages and exudates is important in order to diagnose diabetic retinopathy. Diabetic retinopathy is one of the most significant factors contributing to blindness, and early detection and treatment are important. In this study, hemorrhages and exudates were automatically detected in fundus images without using fluorescein angiograms. Subsequently, the blood vessel regions incorrectly detected as hemorrhages were eliminated by first examining the structure of the blood vessels and then evaluating the length-to-width ratio. Finally, the false positives were eliminated by checking the following features extracted from candidate images: the number of pixels, contrast, 13 features calculated from the co-occurrence matrix, two features based on gray-level difference statistics, and two features calculated from the extrema method. The sensitivity of detecting hemorrhages in the fundus images was 85% and that of detecting exudates was 77%. Our fully automated scheme could accurately detect hemorrhages and exudates.

Paper Details

Date Published: 30 March 2007
PDF: 8 pages
Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65142M (30 March 2007); doi: 10.1117/12.708367
Show Author Affiliations
Yuji Hatanaka, Gifu National College of Technology (Japan)
Toshiaki Nakagawa, Graduate School of Medicine, Gifu Univ. (Japan)
Yoshinori Hayashi, Graduate School of Medicine, Gifu Univ. (Japan)
Tak Co., Ltd. (Japan)
Yutaka Mizukusa, Kowa Co., Ltd. (Japan)
Akihiro Fujita, Kowa Co., Ltd. (Japan)
Masakatsu Kakogawa, Tak Co., Ltd. (Japan)
Kazuhide Kawase, Ogaki Municipal Hospital (Japan)
Takeshi Hara, Graduate School of Medicine, Gifu Univ. (Japan)
Hiroshi Fujita, Graduate School of Medicine, Gifu Univ. (Japan)

Published in SPIE Proceedings Vol. 6514:
Medical Imaging 2007: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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