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Proceedings Paper

Receptor-free nanomechanical sensors
Author(s): Larry R. Senesac; Dechang Yi; Thomas Thundat
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Paper Abstract

Nanomechanical response of molecular adsorption has been demonstrated as the basis for a number of extremely sensitive sensors. Molecular adsorption on microcantilevers results in nanomechanical motion due to adsorption-induced surface stress variation. Chemical selectivity in nanomechanical sensors is achieved by immobilizing receptors on the cantilever surface. Although receptor-based detection has high selectivity for biomolecular detection, it fails when applied to small molecule detection. Nanomechanics, however, offer new possibilities for achieving chemical selectivity that do not use any receptors. For example, small thermal mass or high temperature sensitivity of a cantilever beam could be used for detecting molecular adsorption using photothermal effects and physical property variation due to temperature. Here we describe two such techniques for achieving chemical selectivity without using any receptor molecules.

Paper Details

Date Published: 19 January 2007
PDF: 8 pages
Proc. SPIE 6463, Reliability, Packaging, Testing, and Characterization of MEMS/MOEMS VI, 646302 (19 January 2007); doi: 10.1117/12.708237
Show Author Affiliations
Larry R. Senesac, Oak Ridge National Lab. (United States)
Dechang Yi, Oak Ridge National Lab. (United States)
Thomas Thundat, Oak Ridge National Lab. (United States)

Published in SPIE Proceedings Vol. 6463:
Reliability, Packaging, Testing, and Characterization of MEMS/MOEMS VI
Allyson L. Hartzell; Rajeshuni Ramesham, Editor(s)

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