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Proceedings Paper

Co-registered 3-D ultrasound and photoacoustic imaging using a 1.75D 1280-channel ultrasound system
Author(s): Puyun Guo; John Gamelin; Shikui Yan; Andres Aguirre; Quing Zhu
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Paper Abstract

Photoacoustic imaging is a promising non-invasive imaging technology due to its ability to combine the enhanced contrast of optical absorption with the spatial resolution of acoustic imaging. Co-registered three-dimensional (3-D) ultrasound and photoacoustic imaging takes advantage of both modalities to allow visualization of tissue structures within a volume using simultaneous structural and functional information. 1.75D acoustic arrays are well-suited for this application due to their ability to scan in 3-D volumes rapidly and accurately while maintaining a reasonable system complexity and cost. We have designed, fabricated, and tested a 1.75D 1280-ch ultrasound system for co-registered 3-D ultrasound and photoacoustic imaging. The system features a 1.75D 1280-channel ultrasound array with a center frequency of 5MHz and 80% bandwidth. The electronics includes 1280 high-voltage pulsers, 40 32-to-1 multiplexers, amplification circuitry, and a 40-channel data acquisition circuit. The system is able to drive the entire array simultaneously, and each array element independently, to scan a 3-D volume within +/- 40 degrees in azimuth direction and +/- 10 degrees in elevation respectively. System performance including axial and lateral resolution has been characterized and compared with simulations. Co-registered 3-D ultrasound and photoacoustic imaging has been successfully performed on phantoms with different geometries and contrast.

Paper Details

Date Published: 13 February 2007
PDF: 11 pages
Proc. SPIE 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 643713 (13 February 2007); doi: 10.1117/12.706702
Show Author Affiliations
Puyun Guo, Univ. of Connecticut (United States)
John Gamelin, Univ. of Connecticut (United States)
Shikui Yan, Siemens Molecular Imaging (United States)
Andres Aguirre, Univ. of Connecticut (United States)
Quing Zhu, Univ. of Connecticut (United States)


Published in SPIE Proceedings Vol. 6437:
Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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