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Proceedings Paper

Fabrication of bio-chips by laser ablation
Author(s): Yoshikazu Yoshida
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Paper Abstract

A pulse laser of ultraviolet region was used to form the flow path and so on. Numbers of heat-hardening resin-films and fluoro resins were piled up a soda glass. A laser fabricated a part of the channel at the each film every lamination, and then 3-D structure micro-channel was fabricated. The channel sizes are widths of 10-400&mgr;m and depths of 30-90&mgr;m. Moreover through holes as artificial capillary-vessels are made in the resin having a minimum diameter of 5 &mgr;m and a length of 100 &mgr;m. As bloods were injected into a particle focusing micro-channel, an artificial capillary-vessel, and a micro-separator, then cell sort, erythrocyte deformability, and blood plasma were observed with a microscope, respectively.

Paper Details

Date Published: 13 March 2007
PDF: 8 pages
Proc. SPIE 6458, Photon Processing in Microelectronics and Photonics VI, 64580A (13 March 2007); doi: 10.1117/12.706226
Show Author Affiliations
Yoshikazu Yoshida, Toyo Univ. (Japan)

Published in SPIE Proceedings Vol. 6458:
Photon Processing in Microelectronics and Photonics VI
David B. Geohegan; Craig B. Arnold; Tatsuo Okada; Frank Träger; Jan J. Dubowski; Michel Meunier; Andrew S. Holmes, Editor(s)

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