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Proceedings Paper

Toward computer-aided emphysema quantification on ultralow-dose CT: reproducibility of ventrodorsal gravity effect measurement and correction
Author(s): Rafael Wiemker; Roland Opfer; Thomas Bülow; Patrik Rogalla; Amnon Steinberg; Ekta Dharaiya; Krishna Subramanyan
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Paper Abstract

Computer aided quantification of emphysema in high resolution CT data is based on identifying low attenuation areas below clinically determined Hounsfield thresholds. However, the emphysema quantification is prone to error since a gravity effect can influence the mean attenuation of healthy lung parenchyma up to ± 50 HU between ventral and dorsal lung areas. Comparing ultra-low-dose (7 mAs) and standard-dose (70 mAs) CT scans of each patient we show that measurement of the ventrodorsal gravity effect is patient specific but reproducible. It can be measured and corrected in an unsupervised way using robust fitting of a linear function.

Paper Details

Date Published: 29 March 2007
PDF: 11 pages
Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65140O (29 March 2007); doi: 10.1117/12.705868
Show Author Affiliations
Rafael Wiemker, Philips Research Europe (Germany)
Roland Opfer, Philips Research Europe (Germany)
Thomas Bülow, Philips Research Europe (Germany)
Patrik Rogalla, Humboldt Univ. Berlin (Germany)
Amnon Steinberg, Philips Medical Systems Technologies Ltd. (Israel)
Ekta Dharaiya, Philips Medical Systems N.A. (United States)
Krishna Subramanyan, Philips Medical Systems N.A. (United States)

Published in SPIE Proceedings Vol. 6514:
Medical Imaging 2007: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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