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Proceedings Paper

Labeling the pulmonary arterial tree in CT images for automatic quantification of pulmonary embolism
Author(s): Ralph J. M. Peters; Henk A. Marquering; Halil Dogan; Emile A Hendriks; Albert de Roos; Johan H. C. Reiber; Berend C. Stoel
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Paper Abstract

Contrast-enhanced CT Angiography has become an accepted diagnostic tool for detecting Pulmonary Embolism (PE). The CT obstruction index proposed by Qanadli, which is based on the number of obstructed arterial segments, enables the quantification of PE severity. Because the required manual identification of twenty arterial segments is time consuming, we propose a method for automated labeling of the pulmonary arterial tree to identify the arterial segments. Assuming that the peripheral parts of the arterial tree contain most relevant information for labeling, we propose a bottom-up labeling algorithm exploiting the spatial information of the peripheral arteries. A model of reference positions of the arterial segments was trained using manually labeled trees of 9 patients. To improve accuracy, the arterial tree was partitioned into sub-trees enabling an iterative labeling technique that labels each sub-tree separately. The accuracy of the labeling technique was evaluated using manually labeled trees of 10 patients. Initially an accuracy of 74% was obtained, whereas the iterative approach improved accuracy to 85%. The labeling errors had minor effects on the calculated Qanadli index. Therefore, the presented labeling approach is applicable in automated PE quantification.

Paper Details

Date Published: 30 March 2007
PDF: 11 pages
Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65143Q (30 March 2007); doi: 10.1117/12.705840
Show Author Affiliations
Ralph J. M. Peters, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)
Henk A. Marquering, Leiden Univ. Medical Ctr. (Netherlands)
Halil Dogan, Leiden Univ. Medical Ctr. (Netherlands)
Emile A Hendriks, Delft Univ. of Technology (Netherlands)
Albert de Roos, Leiden Univ. Medical Ctr. (Netherlands)
Johan H. C. Reiber, Leiden Univ. Medical Ctr. (Netherlands)
Berend C. Stoel, Leiden Univ. Medical Ctr. (Netherlands)

Published in SPIE Proceedings Vol. 6514:
Medical Imaging 2007: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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