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Proceedings Paper

Hollow fiber-optic Raman probes for small experimental animals
Author(s): Takashi Katagiri; Yusuke Hattori; Toshiaki Suzuki; Yuji Matsuura; Hidetoshi Sato
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Paper Abstract

Two types of hollow fiber-optic probes are developed to measure the in vivo Raman spectra of small animals. One is the minimized probe which is end-sealed with the micro-ball lens. The measured spectra reflect the information of the sample's sub-surface. This probe is used for the measurement of the esophagus and the stomach via an endoscope. The other probe is a confocal Raman probe which consists of a single fiber and a lens system. It is integrated into the handheld microscope. A simple and small multimodal probe is realized because the hollow optical fiber requires no optical filters. The performance of each probe is examined and the effectiveness of these probes for in vivo Raman spectroscopy is shown by animal tests.

Paper Details

Date Published: 15 February 2007
PDF: 7 pages
Proc. SPIE 6433, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII, 64330O (15 February 2007); doi: 10.1117/12.702664
Show Author Affiliations
Takashi Katagiri, RIKEN The Institute of Physical and Chemical Research (Japan)
Yusuke Hattori, RIKEN The Institute of Physical and Chemical Research (Japan)
Toshiaki Suzuki, RIKEN The Institute of Physical and Chemical Research (Japan)
Yuji Matsuura, Tohoku Univ. (Japan)
Hidetoshi Sato, RIKEN The Institute of Physical and Chemical Research (Japan)


Published in SPIE Proceedings Vol. 6433:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII
Israel Gannot, Editor(s)

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