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Proceedings Paper

Orientation-weighted local Minkowski functionals in 3D for quantitative assessment of trabecular bone structure in the hip
Author(s): H. F. Boehm; H. Bitterling; C. Weber; V. Kuhn; F. Eckstein; M. Reiser
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Paper Abstract

Fragility fractures or pathologic fractures of the hip, i.e. fractures with no apparent trauma, represent the worst complication in osteoporosis with a mortality close to 25% during the first post-traumatic year. Over 90% of hip fractures result from falls from standing height. A substantial number of femoral fractures are initiated in the femoral neck or the trochanteric regions which contain an internal architecture of trabeculae that are functionally highly specialized to withstand the complex pattern of external and internal forces associated with human gait. Prediction of the mechanical strength of bone tissue can be achieved by dedicated texture analysis of data obtained by high resolution imaging modalities, e.g. computed tomography (CT) or magnetic resonance tomography (MRI). Since in the case of the proximal femur, the connectivity, regional distribution and - most of all - the preferred orientation of individual trabeculae change considerably within narrow spatial limits, it seems most reasonable to evaluate the femoral bone structure on an orientation-weighted, local scale. In past studies, we could demonstrate the advantages of topological analysis of bone structure using the Minkowski Functionals in 3D on a global and on a local scale. The current study was designed to test the hypothesis that the prediction of the mechanical competence of the proximal femur by a new algorithm considering orientational changes of topological properties in the trabecular architecture is feasible and better suited than conventional methods based on the measurement of the mineral density of bone tissue (BMD).

Paper Details

Date Published: 3 March 2007
PDF: 5 pages
Proc. SPIE 6512, Medical Imaging 2007: Image Processing, 65124D (3 March 2007); doi: 10.1117/12.702447
Show Author Affiliations
H. F. Boehm, Ludwig-Maximilians-Univ. Munich (Germany)
H. Bitterling, Ludwig-Maximilians-Univ. Munich (Germany)
C. Weber, Ludwig-Maximilians-Univ. Munich (Germany)
V. Kuhn, Ludwig-Maximilians-Univ. Munich (Germany)
F. Eckstein, Ludwig-Maximilians-Univ. Munich (Germany)
M. Reiser, Ludwig-Maximilians-Univ. Munich (Germany)


Published in SPIE Proceedings Vol. 6512:
Medical Imaging 2007: Image Processing
Josien P. W. Pluim; Joseph M. Reinhardt, Editor(s)

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