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Proceedings Paper

Classification of the degenerative grade of lesions of supraspinatus rotator cuff tendons by FT-Raman spectroscopy
Author(s): Bianca Palma Fogazza; Carolina da Silva Carvalho; Sergio Godoy Penteado; Cláudio S. Meneses; Airton Abrahão Martin; Herculano da Silva Martinho
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Paper Abstract

FT-Raman spectroscopy was employed to access the biochemical alterations occurring on the degenerative process of the rotator cuff supraspinatus tendons. The spectral characteristic variations in the 351 spectra of samples of 39 patients were identified with the help of Principal Components Analysis. The main variations occurred in the 840-911; 1022- 1218; 1257; 1270; 1300; 1452; 1663; and 1751 cm-1 regions corresponding to the vibrational bands of proline, hydroxiproline, lipids, nucleic acids, carbohydrates, collagen, and elastin. These alterations are compatible with the pathology alterations reported on the literature. Scattering plots of PC 4 vs PC 2 and PC 3 vs PC 2 contrasted with histopathological analysis has enabled the spectral classification of the data into normal and degenerated groups of tendons. By depicting empiric lines the estimated sensibility and specificity were 39,6 % and 97,8 %, respectively for PC 4 vs PC 2 and 36,0 % and 100 %, respectively for PC 3 vs PC 2. These results indicate that Raman spectroscopy can be used to probe the general tendon quality and could be applied as co adjuvant element in the usual arthroscopy surgery apparatus to guide the procedure and possibly infer about the probability of rerupture.

Paper Details

Date Published: 15 February 2007
PDF: 8 pages
Proc. SPIE 6445, Optical Diagnostics and Sensing VII, 64450S (15 February 2007); doi: 10.1117/12.702203
Show Author Affiliations
Bianca Palma Fogazza, Univ. do Vale do Paraíba (Brazil)
Carolina da Silva Carvalho, Univ. do Vale do Paraíba (Brazil)
Sergio Godoy Penteado, Univ. do Vale do Paraíba (Brazil)
Cláudio S. Meneses, CIPAX-Medicina Diagnóstica (Brazil)
Airton Abrahão Martin, Univ. do Vale do Paraíba (Brazil)
Herculano da Silva Martinho, Univ. do Vale do Paraíba (Brazil)


Published in SPIE Proceedings Vol. 6445:
Optical Diagnostics and Sensing VII
Gerard L. Coté; Alexander V. Priezzhev, Editor(s)

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