Share Email Print
cover

Proceedings Paper

Design and evaluation of a simultaneous fNIRS/ERP instrument
Author(s): Li Li; Peng Du; Ting Li; Qingming Luo; Hui Gong
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Functional Near-Infrared Spectroscopy (fNIRS) is a powerful non-invasive method to measure hemodynamic changes in tissues, while electroencephalography (EEG) provides excellent neuronal-electrical information in functional brain mapping. We developed an fNIRS/ERP instrument which can concurrently monitor the electrical neuronal activation and the hemodynamic response for the study of neurovascular coupling of the human brain. The probe of the instrument consists of 1 LED operating at three different wavelengths (735 nm & 805 nm & 850 nm) and 2 photodiodes (PDs) with the interoptode distance up to 3 cm, and an Ag-AgCl electrode lies in the center of the LED-PD pairs. The four components are encapsulated in a black sponge to decrease the interference of outside light as well as facilitate the placement on the forehead. The signals from the PDs and the electrode separately pass though two adjustable amplify-filter circuits which amplify the weak signals and block the high frequency interferences. A high speed data acquisition board samples the modulated signals under the control of a home-made software. The time resolution of the instrument achieves less than 10ms, which makes it realizable to compare the fNIRS data with the ERP data.

Paper Details

Date Published: 13 February 2007
PDF: 6 pages
Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 643429 (13 February 2007); doi: 10.1117/12.701730
Show Author Affiliations
Li Li, Britton Chance Ctr. for Biomedical Photonics, Huazhong Univ. of Science and Technology (China)
Peng Du, Britton Chance Ctr. for Biomedical Photonics, Huazhong Univ. of Science and Technology (China)
Ting Li, Britton Chance Ctr. for Biomedical Photonics, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Britton Chance Ctr. for Biomedical Photonics, Huazhong Univ. of Science and Technology (China)
Hui Gong, Britton Chance Ctr. for Biomedical Photonics, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 6434:
Optical Tomography and Spectroscopy of Tissue VII
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

© SPIE. Terms of Use
Back to Top