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Proceedings Paper

A high-resolution optofluidic microscope with optical tweezer actuation
Author(s): Xin Heng; Edward Hsiao; Demetri Psaltis; Changhuei Yang
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Paper Abstract

In this paper, we will report our recent development of a new type of OptoFluidic Microscope (OFM) that is capable of delivering resolution beyond the diffraction limit of light. Accurate control of the sample translation is accomplished by adopting an optical tweezer scanner into the system. During the image acquisition, a two-dimensional nanoaperture array defined on a thin aluminum film acts as an array of ultra-fine illumination sources. The imaging system is tested and demonstrated by using polystyrene beads and green algae (Chlamydomonas). Properties of the system are reported and discussed.

Paper Details

Date Published: 19 February 2007
PDF: 7 pages
Proc. SPIE 6441, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V, 644113 (19 February 2007); doi: 10.1117/12.701728
Show Author Affiliations
Xin Heng, California Institute of Technology (United States)
Edward Hsiao, California Institute of Technology (United States)
Demetri Psaltis, California Institute of Technology (United States)
Ecole Polytechnique Federale de Lausanne (Switzerland)
Changhuei Yang, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 6441:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V
Daniel L. Farkas; Robert C. Leif; Dan V. Nicolau, Editor(s)

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